For laboratory research use only. Not for human or veterinary consumption.

Kidney & urinary tract: peptides in published research

Sources checked 2026-10-07 · 6 compounds · 9 cited studies

Scope: Kidneys, bladder and urethra. Each entry names the model and the tissue that a published study looked at, with the citation. It describes what was studied, not what was found, and a listing here is not a claim that a compound does anything in that organ.

ARA-290 (cibinetide)

  • Animal Pigs with unilateral renal ischemia for 45 minutes and reperfusion; glomerular filtration rate over seven days. Published 2013 · PubMed PMID 23302512 ↗

Also listed under: Brain & nervous system, Heart & blood vessels, Gut & digestive tract, Eye

BPC-157

  • Human Pilot study in adults with interstitial cystitis (bladder pain syndrome). Published 2024 · PubMed PMID 39325560 ↗
  • Animal Female rat stress urinary incontinence models; leak point pressure and vesicourethral tissue. Published 2013 · PubMed PMID 23478678 ↗

Also listed under: Brain & nervous system, Heart & blood vessels, Liver, Gut & digestive tract, Skin, Muscle & tendon, Eye

FOXO4-DRI

  • Animal Fast-aging XpdTTD/TTD mice and naturally aged mice; renal function among the measures. Published 2017 · PubMed PMID 28340339 ↗

Also listed under: Heart & blood vessels, Skin, Bone & cartilage, Lungs & airways, Reproductive organs & breast

IGF-1 LR3

  • Animal Rats with acute renal failure after both renal arteries were clamped for 45 min; LR3IGF-I compared with IGF-I. Published 1994 · PubMed PMID 8138750 ↗

Also listed under: Gut & digestive tract, Muscle & tendon, Pituitary & hormone axes

Klotho (α-Klotho)

  • Animal Renal ischemia-reperfusion (acute kidney injury) in mice with different levels of their own Klotho (haploinsufficient, wild-type and Klotho-overexpressing transgenic), and in rats given recombinant Klotho protein; kidney tissue, urine and blood. Published 2010 · PubMed PMID 20861825 ↗
  • Animal Mouse models of acute kidney injury (ischemia-reperfusion) and chronic kidney disease (uninephrectomy plus contralateral ischemia-reperfusion) given recombinant α-Klotho protein; kidney tissue. Published 2017 · PubMed PMID 28131398 ↗
  • Animal & human Mouse chronic kidney disease model in Klotho-overexpressing transgenic and Klotho-haploinsufficient mice (kidney function and Klotho in kidney, plasma and urine), plus urinary Klotho in people at different stages of chronic kidney disease. Published 2011 · PubMed PMID 21115613 ↗

Also listed under: Brain & nervous system, Heart & blood vessels, Muscle & tendon, Bone & cartilage, Eye, Lungs & airways

Semaglutide

  • Human FLOW: randomized placebo-controlled trial in adults with chronic kidney disease (eGFR and urinary albumin-to-creatinine criteria); primary outcome was major kidney disease events. Published 2024 · PubMed PMID 38785209 ↗

Also listed under: Heart & blood vessels, Liver, Pancreas & adipose tissue

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See also: all organ systems · all compound profiles.